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The genetics of Beh?et’s disease in a Chinese population

Shengping Hou, Aize Kijlstra, Peizeng Yang

Frontiers of Medicine 2012, Volume 6, Issue 4,   Pages 354-359 doi: 10.1007/s11684-012-0234-2

Abstract:

Beh?et’s disease is defined as a multisystemic inflammatory disease.et’s disease. To explore the genetic factors for Beh?et’s disease, our group investigated the association of Beh?et’s disease with multiple immune response genes and has identified multiple Beh?et’s disease-related immunoregulatory pathways in the Chinese Han population.

Keywords： Beh?et’s disease     SNPs     immune gene     genetic study    

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Zipfian interpretation of textbook vocabulary lists: comments on Xiao et al.’s Corpus-based research Correspondence

Qiong HU, Ming YUE

Frontiers of Information Technology & Electronic Engineering 2017, Volume 18, Issue 7,   Pages 863-866 doi: 10.1631/FITEE.1700418

Abstract: Xiao et al. (2017)在对比分析4个语料库的基础上，提出国内小学六年级学生的识词率增长不能令人满意的观点，建议人教版小学英语通用教材总词汇在原有726个的基础上再增加903个，并删除twelfth（序数词，第十二）这样的低频词。作为外语教师和语言学家，我们赞同他们应用先进信息技术对传统词表进行评估的做法，但认为这项工作：1. 在构建参考语料库时需重视语料抽样的合理性；2. 在解读词频时需重视齐夫定律（Zipf’s law，即英语词频与词秩成反比）的作用——识字率增长随词汇量增加而减缓的情况是合理的；3. 在提出教材选词策略时，需考虑小学生认知特点和课业负担等现实因素限制，以及语言教育的总体目标，不能随便删除twelfth这样承载文化的词汇；4. 学龄儿童全国通用外语教材编写是项复杂的系统工程，需要各领域专家共同关注。

Keywords： 齐夫定律（Zipf’s law）；语料库；英语；教科书；词表    

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Astrocytes in depression and Alzheimer’s disease

Frontiers of Medicine 2021, Volume 15, Issue 6,   Pages 829-841 doi: 10.1007/s11684-021-0875-0

Abstract: chronic brain diseases may cause psychosocial and cognitive impairment, such as depression and Alzheimer’sdisease (AD).depression and AD has shown that depression might be a prodrome of progressive degenerative neurological disease

Keywords： astrocytes     depression     Alzheimer’s disease     roles     mechanisms    

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Oxidative stress in granulosa cells contributes to poor oocyte quality and IVF-ET outcomes in women with

Qiaohong Lai, Wenpei Xiang, Qing Li, Hanwang Zhang, Yufeng Li, Guijin Zhu, Chengliang Xiong, Lei Jin

Frontiers of Medicine 2018, Volume 12, Issue 5,   Pages 518-524 doi: 10.1007/s11684-017-0575-y

Abstract: In this study, we compared thein vitro fertilization and embryo transfer (IVF-ET) resultsgreatly induced cell apoptosis, which further affected the oocyte quality and reduced the positive IVF-ET

Keywords： PCOS     ROS     granulosa cell     IVF-ET     NADPH oxidase    

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Altered white matter microarchitecture in Parkinson’s disease: a voxel-based meta-analysis of diffusion

Xueling Suo, Du Lei, Wenbin Li, Lei Li, Jing Dai, Song Wang, Nannan Li, Lan Cheng, Rong Peng, Graham J Kemp, Qiyong Gong

Frontiers of Medicine 2021, Volume 15, Issue 1,   Pages 125-138 doi: 10.1007/s11684-019-0725-5

Abstract: This study aimed to define the most consistent white matter microarchitecture pattern in Parkinson’sdisease (PD) reflected by fractional anisotropy (FA), addressing clinical profiles and methodology-relatedSubgroup analyses were conducted considering heterogeneity with respect to medication status, disease

Keywords： Parkinson’s disease     diffusion tensor imaging     fractional anisotropy     meta-analysis     anisotropic effect size–signed    

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Protein phosphatase 2A, a key player in Alzheimer’s disease

Rong LIU, Qing TIAN

Frontiers of Medicine 2009, Volume 3, Issue 1,   Pages 8-12 doi: 10.1007/s11684-009-0017-6

Abstract: In the brains of patients with Alzheimer’s disease (AD), decreased PP2A activities were observed, whichFurther studies are required to disclose the role of PP2A in Alzheimer’s disease.

Keywords： protein phosphatase 2A     Alzheimer’s disease     holoenzyme composition     protein phosphatase 2A inhibitors     Leu309    

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A Micro Peristaltic Pump Using an Optically Controllable Bioactuator Article

Eitaro Yamatsuta, Sze Ping Beh, Kaoru Uesugi, Hidenobu Tsujimura, Keisuke Morishima

Engineering 2019, Volume 5, Issue 3,   Pages 580-585 doi: 10.1016/j.eng.2018.11.033

Abstract: peristaltic pump, and thus determined that the pump could transport microbeads at a speed of 120 μm·s<

Keywords： Tubular structure     Bioactuator     Peristaltic pump     Optogenetics     Biomaterial     Muscle actuator     Tissue engineered     Soft robot    

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Effect of ambient polycyclic aromatic hydrocarbons and nicotine on the structure of Aβ protein

Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 2, doi: 10.1007/s11783-023-1615-2

Abstract:

● B[a]P, nicotine and phenanthrene molecules altered the secondary structure of Aβ42.

Keywords： Polycyclic aromatic hydrocarbons     Nicotine     toxicology     Aβ42 peptide     Alzheimer’s disease    

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Heterogeneity of chronic obstructive pulmonary disease: from phenotype to genotype

Xu Chen, Xiaomao Xu, Fei Xiao

Frontiers of Medicine 2013, Volume 7, Issue 4,   Pages 425-432 doi: 10.1007/s11684-013-0295-x

Abstract:

Chronic obstructive pulmonary disease (COPD) is one of the leading causes of morbidity and mortality

Keywords： chronic obstructive pulmonary disease     heterogeneity     phenotype     genotype     prediction    

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Acupuncture for the management of dry eye disease

Frontiers of Medicine 2022, Volume 16, Issue 6,   Pages 975-983 doi: 10.1007/s11684-022-0923-4

Abstract: The effectiveness of using acupuncture for dry eye disease (DED) is controversial.outcomes of interests were (1) to evaluate the efficacy of acupuncture in improving the ocular surface disease

Keywords： dry eye disease     xerophthalmus     acupuncture    

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Exploration of Strategies for Chronic Disease Prevention and Control and Relevant System Development

Long-de Wang

Frontiers of Engineering Management 2015, Volume 2, Issue 1,   Pages 2-12 doi: 10.15302/J-FEM-2015002

Abstract: acceleration of industrialization and urbanization, along with population aging and rapid changes of people’sthe status of major chronic diseases in China, analyzing the key issues and key factors in chronic diseasethe previous projects, this paper proposes the following recommendations as strategies for chronic diseaseWork norms and requirements will then improve the performance and efficiency in chronic disease prevention

Keywords： chronic disease prevention and control     strategy and system construction    

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Minimal residual disease in solid tumors: an overview

Frontiers of Medicine 2023, Volume 17, Issue 4,   Pages 649-674 doi: 10.1007/s11684-023-1018-6

Abstract: Minimal residual disease (MRD) is termed as the small numbers of remnant tumor cells in a subset of patients

Keywords： MRD     solid tumor     CTC     ctDNA    

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Multislice computed tomography angiography in the diagnosis of cardiovascular disease: 3D visualizations

Zhonghua Sun

Frontiers of Medicine 2011, Volume 5, Issue 3,   Pages 254-270 doi: 10.1007/s11684-011-0153-7

Abstract: computed tomography (CT) has been widely used in clinical practice for the diagnosis of cardiovascular diseaseangiography has been recognized as the method of choice for detecting and diagnosing head and neck vascular diseaseIn patients with suspected coronary artery disease, although invasive coronary angiography still remainsThe imaging diagnosis of cardiovascular disease is based on a combination of two-dimensional (2D) andan overview of the diagnostic performance of various 2D and 3D CT visualizations in cardiovascular disease

Keywords： cardiovascular disease     multislice computed tomography     three-dimensional reconstruction     diagnosis     visualization    

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Zooming in and out of ferroptosis in human disease

Frontiers of Medicine 2023, Volume 17, Issue 2,   Pages 173-206 doi: 10.1007/s11684-023-0992-z

Abstract: ferroptosis and its regulatory pathways could provide additional strategies for the management of these disease, we summarize the progress in the research into ferroptosis and its regulatory mechanisms in human diseaseWe also discuss our perspectives on the future directions in the targeting of ferroptosis in human disease

Keywords： ferroptosis     human disease     iron metabolism     lipid peroxidation     antioxidation    

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Atomistic characterization of binding modes and affinity of peptide inhibitors to amyloid-

Fufeng LIU,Wenjie DU,Yan SUN,Jie ZHENG,Xiaoyan DONG

Frontiers of Chemical Science and Engineering 2014, Volume 8, Issue 4,   Pages 433-444 doi: 10.1007/s11705-014-1454-6

Abstract: The aggregation of amyloid -protein (A ) is tightly linked to the pathogenesis of Alzheimer’s disease

Keywords： Alzheimer’s disease     amyloid β-protein     peptide inhibitors     protein-protein interaction     molecular    

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Title Author Date Type Operation

The genetics of Beh?et’s disease in a Chinese population

Shengping Hou, Aize Kijlstra, Peizeng Yang

Journal Article

Zipfian interpretation of textbook vocabulary lists: comments on Xiao et al.’s Corpus-based research

Qiong HU, Ming YUE

Journal Article

Astrocytes in depression and Alzheimer’s disease

Journal Article

Oxidative stress in granulosa cells contributes to poor oocyte quality and IVF-ET outcomes in women with

Qiaohong Lai, Wenpei Xiang, Qing Li, Hanwang Zhang, Yufeng Li, Guijin Zhu, Chengliang Xiong, Lei Jin

Journal Article

Altered white matter microarchitecture in Parkinson’s disease: a voxel-based meta-analysis of diffusion

Xueling Suo, Du Lei, Wenbin Li, Lei Li, Jing Dai, Song Wang, Nannan Li, Lan Cheng, Rong Peng, Graham J Kemp, Qiyong Gong

Journal Article

Protein phosphatase 2A, a key player in Alzheimer’s disease

Rong LIU, Qing TIAN

Journal Article

A Micro Peristaltic Pump Using an Optically Controllable Bioactuator

Eitaro Yamatsuta, Sze Ping Beh, Kaoru Uesugi, Hidenobu Tsujimura, Keisuke Morishima

Journal Article

Effect of ambient polycyclic aromatic hydrocarbons and nicotine on the structure of Aβ protein

Journal Article

Heterogeneity of chronic obstructive pulmonary disease: from phenotype to genotype

Xu Chen, Xiaomao Xu, Fei Xiao

Journal Article

Acupuncture for the management of dry eye disease

Journal Article

Exploration of Strategies for Chronic Disease Prevention and Control and Relevant System Development

Long-de Wang

Journal Article

Minimal residual disease in solid tumors: an overview

Journal Article

Multislice computed tomography angiography in the diagnosis of cardiovascular disease: 3D visualizations

Zhonghua Sun

Journal Article

Zooming in and out of ferroptosis in human disease

Journal Article

Atomistic characterization of binding modes and affinity of peptide inhibitors to amyloid-

Fufeng LIU,Wenjie DU,Yan SUN,Jie ZHENG,Xiaoyan DONG

Journal Article